Multiple regions of NSR1 are sufficient for accumulation of a fusion protein within the nucleolus.

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Multiple regions of NSR1 are sufficient for accumulation of a fusion protein within the nucleolus

NSR1, a 67-kD nucleolar protein, was originally identified in our laboratory as a nuclear localization signal binding protein, and has subsequently been found to be involved in ribosome biogenesis. NSR1 has three regions: an acidic/serine-rich NH2 terminus, two RNA recognition motifs, and a glycine/arginine-rich COOH terminus. In this study we show that NSR1 itself has a bipartite nuclear local...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1993

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.123.5.1081